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Synergistic or antagonistic interactions between compounds can alter their individual pharmacokinetics, necessitating careful adjustments and extensive preliminary research for each compound
The results showed that Alefacept effectively maintained endogenous insulin production, decreased the exogenous insulin requirement, and notably lowered the chance of major hypoglycemic events by 50% during the 2-year study period [67]
doi: 10.1080/00365513.2019.1568150 70
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