PEG modification increased the stability of protein and peptide drugs, increased the solubility, reduced the immunogenicity, prolonged the residence time in blood, reduced the protease degradation, and reduced the frequency of drug use
While GLP-1 medications were originally developed for Type II diabetes management, they are now widely used for metabolic health and weight management in non-diabetic patients who have obesity, insulin resistance, or weight loss resistance
That's not a small dipthat's your profit margin walking out the door
Considering the totality of evidence from clinical trials, post-marketing reports and observational studies, alongside the generally low incidence rate of NAION, Novo Nordisk believes that the benefit-risk profile of semaglutide remains favorable, the spokesperson said.
The researchers included the costs of medication, other medical therapy, and worker productivity in their analysis