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To examine whether the chemical conjugation of MK-801 to GLP-1 mitigates the adverse hyperthermic and hyperlocomotive effects of MK-801, mice were subjected to body temperature measurements and open-field behavioural tests after chronic and acute drug administration, respectively

The contrast with metabolic disease is the sharpest framing

Its dual action on both the gut lining and connective tissues makes it especially relevant in modern integrative medicine

Estimands used to assess treatment efficacy In line with regulatory guidance, the STEP trials were designed to report results using two estimands

[DOI] [PubMed] [Google Scholar] 6.Polidoro G, Di Ilio C, Arduini A, et al