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Close collaboration between patients and healthcare providers is crucial to develop an individualized treatment plan that addresses the gallbladder issue while considering the patients broader health needs and treatment goals
doi: 10.1136/bmjopen-2023-081401 [DOI] [PMC free article] [PubMed] [Google Scholar] 83.Chuong V, Farokhnia M, Khom S, et al
Understanding why requires appreciating how weight loss itself affects thyroid function: Weight loss reduces leptin levels , which can decrease TRH (thyrotropin-releasing hormone) secretion from the hypothalamus, potentially lowering TSH Improved insulin sensitivity may alter thyroid hormone metabolism and conversion of T4 to T3 Reduced inflammation from fat loss can change the thyroid hormonal milieu Changes in body composition affect thyroid hormone distribution and binding A retrospective study of over 21,000 patients found that hypothyroid individuals using semaglutide experienced modest TSH decreases alongside weight loss
Congressional Research Service
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