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The niacinamide simply comes along for the ride at whatever concentration the new compound provides
While all approved sites (abdomen, upper arm, thigh, buttock) are effective, some studies show slightly better absorption from the abdomen
Tryptophan-rich diet ameliorates chronic unpredictable mild stress induced depression- and anxiety-like behavior in mice: the potential involvement of gut-brain axis
References American Red Cross
The fix: move to a different site each week, and within a region like the abdomen, rotate through quadrants so each small area gets three to four weeks to recover
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