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Gut 44 , 8186 (1999)

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Significant reduction of headache attacks frequency, intensity, duration and monthly days with acute medication intake has been observed both complex MOH (58.5%) and simple MOH (41.5%) after the first, third and sixth month of preventive treatment with CGRP-mAbs ( p 0.05)

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Purity is calculated by measuring the area of the main peak as a percentage of the total area of all peaks on the chromatogram