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TRX-1 secreted into the extracellular space is mainly in the oxidized form

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Guo L, Yang X, Zhang Y, Xu X, Li Y (2022) Effect of exercise on cognitive function and synaptic plasticity in Alzheimers disease models: a systematic review and meta-analysis

Galasso M, Gambino S, Romanelli MG, et al

found that Exos released from pericardial adipose tissue interacted with iron regulatory protein 2, helping to protect cardiomyocytes from ferroptosis while maintaining iron homeostasis disrupted by Adipsin [153]