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Multiple comparisons between different groups was performed using Analysis of Variance (ANOVA) followed by Dunetts Multiple comparison Test

Later studies have gone on to expand on the importance of the Nrf2/ARE complex in epilepsy in a number of animal models such as pentetrazol [36], lithium-pilocarpine [37] and kainate [38]

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Impaired individuals exhibit hypomethylation of CpG sites in the CCL11 promoter region, which are then hypermethylated upon supplementation with B12 In impaired individuals, three CpG sites exhibited hypomethylation when compared to the non-impaired group