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Full publication of combination-therapy data is awaited, however interim analysis from the phase II COURAGE trial (NCT06299098) found 3.3% reduction in lean mass of obese patients treated with the combination of trevogrumab and semaglutide, compared with 6.5% reduction with semaglutide alone [70]

By understanding the key distinguishing characteristics of Semaglutide GLP-1 and Liraglutide, we can better tailor our treatment plans to each patients unique needs and preferences, thereby improving outcomes and patient satisfaction

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Mollan SP, Tahrani AA, Sinclair AJ