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2018 Apr 18;20(5):15

If you find the 45 unit mark uncomfortably small to read, the honest options are (a) use a finer-gradation syringe, or (b) follow a protocol built around the 50 mg vial, whose larger draw is more forgiving not to freehand a bigger volume from the 10 mg vial, which would silently overdose relative to the documented figure

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Pain through biceps, in elbow joint, forearm down through wrist

Taking progesterone while taking estrogen is key because it reduces this thickening and brings the uterine cancer risk back to baseline