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The similarly elevated levels and independent prognostic utilities of GDF15 in HFrEF and HFpEF suggest that beyond haemodynamic stress (NT-proBNP), inflammatory injury (GDF15) may play an important role in both HF syndromes.57 Extracellular Matrix and Fibrosis Pro-collagen Propeptides One of the hallmarks of interstitial fibrosis is deposition of types I and III fibrillar collagen

The samples were then cleaned in xylene, embedded, and blocked in liquid paraffin wax after being dehydrated in increasing concentrations of ethyl alcohol