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292 The interaction between mechanical forces and cellular mechanotransduction mechanisms, such as the integrin-mediated activation of focal adhesion kinase (FAK) and the subsequent activation of the MAPK/ERK pathway, plays a crucial role in ligament adaptation and repair

References Risbud MV, Schaer TP, Shapiro IM: Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord

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Given the emerging evidence on the gutbrainmuscle axis, the impact of probiotics on central fatigue, motivation, and cognitive resilience should be better elucidated