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Larger changes (5+ letters, visual field changes exceeding test-retest variability, OCT thickness changes over 5-10 microns) more clinically relevant

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Because cellular damage of endothelial cells exposed to homocysteine may be prevented by pretreatment of cells with catalase, which allows the detoxification of hydrogen peroxide that freely crosses the cell membrane (Starkebaum and Harlan, 1986

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