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Preparation Condition 1 (heparin deproteinization 80 o C) vs

Patients will still need to be monitored for both local effects (mucosal changes or olfactory disturbances) and any systemic absorption effects (e.g., serum iron and blood counts) when intranasal chelation is tested in clinical studies

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Sun, Y., et al

It is not clear whether findings in rodent studies are applicable to humans