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However, WADA is currently monitoring and evaluating the use of GLP-1 agonists by athletes to determine if they should be prohibited in the future

Weight loss is the most visible change, with clinical trials demonstrating average reductions that vary by medication: approximately 5-10% with liraglutide (Saxenda), 15-17% with semaglutide 2.4mg (Wegovy) in the STEP trials, and up to 20% with higher doses of tirzepatide in the SURMOUNT programme

Over time, this can lead to premature shedding and a lack of new growth

Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has received significant attention for its weight-loss benefits and therapeutic potential in diabetes management

Creatine serves as an anabolic signal for muscle growth, acting as the chemical messenger that links increased muscle activity with the production of new muscle tissue.35,36 The most used and studied supplemental form of creatine is creatine monohydrate