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Not one of these drugs are curative, and their long-term use often causes severe side effects including cancer

TABLE 2 The inhibitors of signaling pathways in ferroptosis

87 : 11521164 Ferrari A, Hoerndli F, Baechi T, Nitsch RM and Gotz J (2003) Beta-amyloid induces paired helical filament-like tau filaments in tissue culture

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The DA Gsta4 rat was thus designed and used to over-express Gsta4 both in primary cultures and in in vivo models in which siRNA towards Gsta4 was used as a knock-down tool