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2), is the average fluid/cell velocity (since the fluid moves at the same speed as the cell), A is the cross-sectional area and R is the hydraulic resistance (i.e., the external load that resists cell/fluid movement) which, for rectangular channels, is proportional to the channel length L

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In addition, kidney weight was markedly reduced in GH-treated and untreated JAK2 -/- mice compared to controls, indicating the importance of circulating IGF-1 in kidney growth, whereas locally produced IGF-1 seems not to have a significant impact on kidney growth

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It is high-risk, uncontrolled human self experimentation