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Phentermine works faster appetite suppression is noticeable within days but the effect is stimulant-based rather than hormonal, does not improve blood sugar or cardiovascular outcomes, and carries different contraindications and side effects

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It activates melanocortin receptors in the brain, particularly the MC4 receptor , which plays an important role in regulating hunger, satiety, and energy balance

Weight loss achieved before pregnancy often improves fertility outcomes and reduces pregnancy complications like gestational diabetes