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We conclude that both PM signatures identify CMS4 tumours and that the vast majority of PM belong to CMS4

An in vitro study carried out on a vincristine-resistant human colorectal carcinoma cell line had demonstrated that curcumin was not only toxic to the cancer cells in a dose-dependent manner, as the concentration started to rise from 25 M onwards, but also could reverse their sensitivity to drugs such as fluorouracil, vincristine, hydroxycamptothecin, and cisplatin [241]

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Porokhovnik LN, cape BM, yaeo A, Chudakova YuM, Ershova ES, Veiko NN, Gorbachevskaya NL, Mamokhina U, Sorokin A, Basova AY, Lapshin MS, Izhevskaya VL, Kostyuk SV (2023) Association of NEF2L2 Rs35652124 polymorphism with Nrf2 induction and genotoxic stress biomarkers in autism