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As mentioned above, MIEAP expression is defective not only in oncocytic thyroid tumors but also in conventional thyroid cancers in which BRAF V600E is the main driver mutation, and our results indicate that mitophagy is critical for suppressing carcinogenesis in thyroid cancers in general

Mechanistically, the inhibition of lncRNA A330074k22Rik by HDG markedly suppresses the Axin2/-catenin pathway, thereby downregulating the inflammatory response associated with AKI

These toxins cause oxidative stress and can damage DNA, mitochondria, and cell membranes

(4) mass-transfer limitations between enzymes and substrates (Luckarift et al., 2004