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Clinical Context Relevant to GLP-1 Treatment Discussions in 2026 GLP-1 receptor agonists like semaglutide represent a class of medications originally developed for type 2 diabetes management that have demonstrated meaningful effects on weight management in clinical research

"This also continues to add shame, guilt and pressure to people whose body size and appearance does not align with those ideals but also, for all those people who do." Serena Williams, a 23-time Grand Slam champion and celebrated Olympian, said she wanted to use the drug openly to dispel "stigma"

Alrasheedi AA et al

Compared with other neuropsychiatric illnesses, most studies on the effects of GLP-1RAs in psychotic disorders seem to have focused so far on their potential use to counteract the cardiometabolic side effects due to antipsychotic medications

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