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In more advanced cases, the condition can lead to infection, intestinal rupture, sepsis, and even death

Therefore, the need for Se supplementation to reduce disease incidence and delay disease progression in people with low baseline Se status has attracted the interest of researchers

Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

Herman et al., 2023

Lee JY, Kang CH (2022) Probiotics alleviate oxidative stress in H2O2-exposed hepatocytes and t-BHP-induced C57BL/6 mice (Article)