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The funder(s) did not have any role in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in the decision to submit the article for publication

Understanding how these medications work helps explain why certain gastrointestinal symptoms may occur during treatment

For those interested in comparing across categories, the peptides vs TRT comparison and peptides vs SARMs comparison provide additional context

Psychopharmacology 240 , 12871298 (2023)

Retatrutide adds GIP and glucagon receptor activity on top of GLP-1 signalling, which may support broader metabolic effects and stronger body-composition outcomes than semaglutide alone