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Among them, specifically targeting the downstream mediators of c-Met involved in tumor progression is a promising method, including the Grb2 SH2 domain, Src, MAPK, STAT3, Shp2 (Liu et al., 2018), and Fak (Jo et al., 2015)
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In contrast, CTS secondary to RA can lead to compression of the median nerve within a short time due to the inflammatory response of the synovium
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