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Differences in study duration and patient populations complicate direct comparison, but the mechanistic rationale and sheer magnitude of effect strongly favor Retatrutide for monotherapy applications

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The median age of the SCD group was 64 (IQR: 8) years and 66 (8.8) years for the MCI group, which was significantly younger than the HC group (74 4 years) ( p 1 H-MRS and Pittsburgh Compound-B PET