glp-1 and liver Frontiers Effects of GLP-1 receptor agonists

Orforglipron, a once-daily oral GLP-1 pill, led to an average weight loss of 11.2% over 72 weeks, along with improvements in blood pressure, triglycerides, and cholesterol

Although it has a minor effect on gastric emptying time, the most common side effects are nausea and vomiting

The medications come with detailed inserts that explain how to store the medication properly

The second part of the Phase 2 study will investigate MariTide beyond 52 weeks to evaluate further weight loss, weight maintenance through lower dosing, and weight loss durability after discontinuation

And this year, competitor Eli Lilly is slated for approval