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41 An observational study from Naples included 85 COPD patients with at least 1 episode of exacerbation in the previous year, who were treated for 1 year with a daily dose of 2.7 g carbocisteine lysine

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Injectable glutathione is not recommended for general use as it can have serious side effects, and should only be administered under the supervision of a qualified medical professional

also showed significant increases in serum concentrations of asymmetric dimethylarginine (ADMA), enhanced inhibition of NOS, enhanced catabolism of Arg, increased levels of ornithine (Orn) and proline (Pro), and decreased Arg/Orn ratio in patients with asthma and obstructive sleep apnea (OSA)