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Otherwise, instead of the standard 2 copies of the gene, you have FOUR copies of the gene, which would be beyond unusual

Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG, Boers GJ, den Heijer M, Kluijtmans LA, Heuvel van den LP, et al: A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

The practical implication: if you are choosing between semaglutide and tirzepatide based solely on published trial outcomes (15% vs 20% weight loss), you are optimizing the wrong variable

Food sits in your stomach longer

doi:10.20463/pan.2023.0027 Johnston, C S, et al