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This interaction site is less defined but comprises the glutathione moiety of Grx(SSG), parts of helix 3, and a conserved lysine/arginine residue that also contributes to the scaffold site 14,15

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GLP-1 has also been shown to regulate peripheral arterial blood flow via signals from the CNS [33, 120]

Data availability The data that support the findings of this study are openly available in TCGA database of PTCs utilizing the Firehouse web browser from the Broad Institute ( using TIMER2.0 ( a computational software for analyses of tumor immunologic, clinical, and genomic features 35