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On the other hand, a series of positive effects have been described in pathways involved in vascular atherogenesis, endothelial function [7, 10] and ventricular contractility [11]

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The results showed a significant increase in skin density and thickness, with a 67% reduction in wrinkle volume and improved elasticity, as measured by ultrasound and profilometry (Leyden et al., 2002)

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