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Our results showed that HL7702 cells exposed to 300 M H 2 O 2 for 12 h showed a significant reduction in PPAR- expression levels, indicating the disturbed lipid homeostasis might occur in H 2 O 2 -damaged HL7702 cells

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Clinical cancer research: an official journal of the American Association for Cancer Research

ROS also induce the release of matrix metalloproteinases (MMPs), enzymes that damage the extracellular matrix and affect tissue integrity (Bryan et al., 2012)

Clairet, A