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Martin JA, Pereda J, Martinez-Lopez I, Escrig R, Miralles V, Pallardo FV, et al

Endothelial cells are considered responsible for the growth and function of blood vessels that supply nutrition to hair follicles and skin cells

Body weight remains a primary outcome measure, with different continuation criteria depending on the indication

Monitoring ensures protocol safety

The selected dose range of the study drugs was as recommended for standard therapeutic maintenance treatment, and subjects were dose escalated to semaglutide 1.0 mg steady state to investigate potential interactions at the highest intended treatment dose