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Mitochondrial glutamate is subsequently converted into alpha-ketoglutarate (-KG) by glutamate dehydrogenase 1 (GLUD1 or GDH1) or by several mitochondrial aminotransferases, including glutamic-pyruvic transaminase 2 (GPT2) and glutamic-oxaloacetic transaminase 2 (GOT2)

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In der klinischen Forschung, der Anti-Aging-Medizin und in fortgeschrittenen Fitnesskreisen wird sie in erster Linie fr eine aggressive, zielgerichtete Fettoxidation, die Optimierung der zellulren Energie und eine neuroprotektive kognitive Verbesserung eingesetzt