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Dihexa has been studied in preclinical models of cognitive function, Alzheimers-like neurodegeneration, and dendritic spine formation, where it has been reported to promote functional synaptogenesis with high potency in neurotrophic assays

1395u(o)(1)(C)) (that is, drugs or biologicals billed by a physician, supplier, or any other person and not paid on a cost or prospective payment basis) furnished on or after January 1, 2005

NS, no significant difference

This approach not only eliminates the need for the addition of allopurinol, it may even allow further upward titration of thiopurine doses to achieve the desired efficacy with little to no risk of adverse drug reactions (Weyer et al., 2001)

Lightbody et al ., Reference Lightbody, Davis and Austin2016)