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Gut microbiome-produced bile acids influence glucose and lipid metabolism, energy balance, and inflammation via FXR and TGR5 receptor signaling, thus, alterations in bile acid profiles may disrupt these pathways and contribute to metabolic disease [219]

Sequencing determines which diagnosis code appears first on the claim, and it varies depending on the clinical relationship

From Figure 8, TMRM fluorescence decreased significantly after atorvastatin treatment, manifesting that atorvastatin caused a breakdown of membrane potential

Charted: Shifts in America's leading causes of death

Our results demonstrated that LPS- exposure induced the inflammatory response, including cytokine expression (IL6, IL-1, TNF) in macrophages, along with Trp-catabolic enzymes IDO1 and associated catabolites Kyn levels in both THP1 and primary KCs