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Variants in GLP1R (rs6923761) and FTO (rs9939609) may influence how effectively semaglutide works for your individual metabolism and thyroid-driven obesity

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## Side Effects: An Honest Assessment The side effect profile is similar to other incretin therapies, with one addition: **Common GI effects:** Nausea (24-35%), diarrhea (15-25%), constipation (10-20%), vomiting (10-15%)

Meanwhile, in the End of Obesity clip, Randy wakes the next day shocked that he feels rejuvenated after a night of doing a hard drug, and unsurprisingly hes lost his appetite