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A spokesperson for telemedicine platform Midi, which has been advertising GLP-1 microdoses on Instagram, said health risks from being overweight, like cardiovascular disease, can begin at BMIs lower than 27 and the shots have a range of benefits like improving fatty liver disease and easing sleep apnea symptoms

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Those with lower starting body mass index (BMI) or those who lose weight rapidly may notice temperature changes more acutely

Stopping treatment when needed: In certain situations, like pregnancy, pancreatitis, severe allergic reactions, or very low BMI (18.5 or below), treatment may be fully discontinued