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However, GS-R mice retained a considerable amount of hydrophilic bile acids: -muricholic acid (MCA), MCA, and ursodeoxycholic acid (UDCA) in their bile (25%), but less hydrophobic DCA

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For instance, bone marrow MSC-derived exosomes (BMSC-Exos) downregulate METTL3 expression, disrupt the m6A-mediated stabilization of ACSL4 mRNA, and ultimately reduce intracellular Fe + , ROS, and lipid peroxidation