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10.1002/jbmr.2564 Summary Keywords glucagonlike peptide1 receptor agonist, randomized controlled trial, older adults, bone mineral density, bone turnover Citation Dinkla L, Beavers KM, Robbins R, Akpalu D, Wherry SJ, Miller G, Beavers DP, Espinoza S, Trejo J, Stepanenko A and Cortes TM (2025) Bone mineral density and turnover response to GLP-1 receptor agonists in older adults with overweight/obesity and prediabetes/type 2 diabetes: a 20-week pilot trial post hoc analysis
We have previously identified a compound YMU1, an inhibitor of thymidylate kinase (TMPK), which increased doxorubicin sensitivity of cancer cells by causing DNA repair toxicity 19,20
Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern
They may suit patients who: Prefer a time-limited device rather than long-term medication Need appetite reset and portion control support Are unsuitable for GLP-1-based therapy Typical outcomes range between 1015% total body weight loss over 612 months, with stronger results when structured aftercare is provided
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