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The FDA has approved various formulations for different indications based on clinical trial evidence

They are also highly unstable, often genetically modified (GMO), and often full of unhealthy additives

Patients currently using compounded semaglutide or tirzepatide should discuss transitioning to FDA approved formulations with their healthcare provider

Medication FAQs What is Rybelsus used for

This claim builds on research from Harvard published in July 2024, which found a significantly increased risk of NAION among semaglutide users, followed by additional studies in January 2025 and warnings from the Danish Medicines Agency