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Tirzepatide, known as Mounjaro for diabetes and recently approved as Zepbound for weight loss, is a newer medication that acts on two key hormones: GLP-1 and GIP

GLP-1 stands for glucagon-like peptide-1 , which is a hormone produced in the gut in response to food to help control glucose metabolism and appetite signals in the brain

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Shifting the schedule earlier than recommended can restart this adjustment cycle and undo any tolerance you've built up