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Interestingly, two cannabinoid receptor-mediated signaling cascades have been identified: one is PREG sensitive and targets the vesicular protein Munc-18-1, thereby depressing transmitter release
10.1126/science.aad0489 15 Ben-SahraI.ManningB
The wide range of health benefits associated with weight loss among obese individuals has led researchers to investigate different mechanisms and identify pharmacological targets to treat obesity
According to Murray et al
The heterogenous clinical presentations, complicated diagnostic criteria, limited provider knowledge and experience, and few diagnostic tools and therapeutic targets require patients to be evaluated by many subspecialists
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