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GLP-1 Pipeline Update: August 2025 Quarterly view of the GLP-1 pipeline and anticipated indications Editorial team Maryam Tabatabai, PharmD Editor-In-Chief Associate Vice President, Clinical Information Carole Kerzic, RPh Executive Editor Drug Information Pharmacist Principal Nicole Kjesbo, PharmD, BCPS Executive Editor Clinical Program Development Director Senior, Pipeline DISCLAIMER The drug pipeline is fluid

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In addition, both AICAR and RSVa SIRT1 activatorhave demonstrated efficacy in promoting mitochondrial adaptation and biogenesis, thereby reducing TEC injury and renal fibrosis in preclinical studies (Morigi et al., 2015