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In addition, genes involved in TG synthesis and lipolysis (for example, Gpat3, Lpin1/2, Plin5 , and Ces1d/b ) were downregulated in the livers of SLC25A45 KO mice, whereas fatty acid synthesis and elongation (for example, Acacb, Elovl1,2,6 ) were upregulated in the SLC25A45 KO livers ( Fig
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We previously produced the App NL-G-F/NL-G-F -KI ( App NL-G-F ) mouse strain using genomic DNA of introns 15 to 17 of mouse APP, which humanized the A sequence, and introduced KM670/671NL (Swedish), I716F (Iberian), and E693G (Arctic) mutations 41
MMPs in learning and memory and neuropsychiatric disorders
In preclinical cell-based models, hCG is used to interrogate Leydig cell responsiveness, CYP enzyme induction kinetics, and receptor desensitisation and internalisation dynamics
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