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Skin irritation, redness, and temporary dryness at the application site are the most commonly mentioned issues

Psychiatry 57 , 271292 (2016)

TSC2 forms a heterodimeric complex with TSC1 that suppresses the mTOR complex 1 (mTORC1) activity by inhibiting the small GTPase Rheb, an essential mTORC1 activator [263]

Appropriate caution should be exercised while treating severe megaloblastic anemia with cyanocobalamin as intense treatment may lead to hypokalemia and sudden death