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doi: 10.1172/jci.insight.140327 44 ArmstrongCWMcGregorNRSheedyJRButtfieldIButtHLGooleyPR

(1993) investigated IGF-1 LR3 in animal models and demonstrated that its reduced IGFBP binding resulted in enhanced bioactivity compared to native IGF-1 at equivalent doses [2]

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