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When the blood cannot be seen with the naked eye, its called microhematuria.) Possible causes of blood in the urine include: Urinary tract infection (UTI) Kidney infection Infections in the bladder, urethra, or prostate Trauma to the urinary tract Kidney stones Kidney cysts Bladder cancer Kidney cancer Prostate cancer Vaginal bleeding Endometriosis Enlarged prostate (benign prostatic hyperplasia) Benign (not cancerous) tumors Hemophilia Sickle cell disease Hard exercise, such as distance running Sexual activity If you suspect there is blood in your urine, see your doctor as soon as possible

In an autocrine mechanism, SASP factors reinforce the cellular senescence of the senescent cells themselves, while in a paracrine mechanism, they are responsible for inducing senescence in surrounding cells [35]

a , C57BL/6 J mice were infected via intravenous (i.v.) tail vein injections and intraperitoneally treated with 10 mg/kg rifampicin (Rif) (q.d.) or 100 mg/kg KL1 (b.i.d.) at 6 h post-infection (hpi) for 2 days

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