10.1007/s12035-014-8705-x [DOI] [PubMed] [Google Scholar] Moyse E., Krantic S., Djellouli N., Roger S., Angoulvant D., Debacq C., et al
Liberzon, A
Let me close by saying that I am a nerd with a passion for researching all evidence and listening to all sides of an argument in forming my beliefs
The wound healing cascade and GHK-Cu: Normal wound healing occurs in four overlapping phases: Hemostasis clotting Inflammation immune cell recruitment Proliferation new tissue formation Remodeling scar maturation GHK-Cu appears to favorably influence phases 2, 3, and 4 simultaneously: In the inflammatory phase , it reduces pro-inflammatory cytokines (IL-6, TNF-) while preserving necessary immune signaling In the proliferative phase , it stimulates keratinocyte migration and fibroblast proliferation, accelerating epithelial coverage In the remodeling phase , it promotes type I collagen deposition over type III (scar) collagen, leading to better scar outcomes This multi-phase tissue repair activity makes GHK-Cu a compound of interest when studied alongside other regenerative peptides
The peptide component further enhances its efficacy, working synergistically with other vitamins to provide comprehensive wellness benefits that go beyond simple vitamin supplementation
