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GHK-Cu exerts its effects primarily through gene expression modulation, influencing approximately 31% of the human genome by upregulating genes involved in antioxidant responses, DNA repair, protein metabolism, and cellular growth while downregulating inflammatory mediators, fibrinogen synthesis, and pathological processes including cancer metastasis
In the current literature, the spontaneously hypertensive rats (SHR) is one of the most widely-used and validated animal models of ADHD [29, 30]
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