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Antioxidants are free radical scavengers because they prevent or slow damage to cells caused by free radicals, which are unstable molecules that the body produces as a reaction to environmental and other pressures (antioxidants article)

Antimicrob Agents Chemother 1989;33:1841-4

The absence of allosteric modulation from the RAMP ECD allows the CTR ECD to adopt a conformation that sits further from the receptor TMD than the position observed in the consensus cryo-EM map